MTHFR testingBy Alane Archer, ND, CNC

MTHFR is the abbreviation for methylenetetrahydrofolate reductase which has a lot to do with folate, folic acid, homocysteine and b vitamins. Several people are concerned and they should be, about whether or not they have a genetic mutation for this necessary nutrient. MTHFR has to do with whether your body uses B vitamins correctly or not. It is also required to convert homocysteine to Methionine which the body needs for proper metabolism and muscle growth which is required for glutathione to be created.

There are TWO main variants within the genetic mutations. Having just one (heterozygous) is unlikely to lead to health issues. But some people have TWO, mutations (homozygous) which can lead to health concerns. One is called “C677T,” and another is called “A1298C”. These mutations are inherited, so if a child has TWO then he got it from his parents. At conception, you receive one copy of the MTHFR gene from each parent. If both parents have mutations, your risk is higher.

Some symptoms of MTHFR Testing deficiencies:
heart disease, depression, OCD, anxiety, bipolar, some cancers, pain, fatigue, nerve pain, migraines, miscarriages

What is homocysteine? It is an amino acid and breakdown product of protein metabolism that, when present in high amounts, has been linked to a higher risk level of heart disease, heart attacks, and strokes. Homocysteine can also lead to a higher plaque level in the arteries and also puts people at risk for Alzheimer’s disease.

This is what we test for
* MTHFR Testing – both of the mutations.
*Comprehensive vitamin/mineral testing that is intracellular and extracellular to check the needed nutrients that involve MTHFR. These include B vitamins, folate, choline, B6, Riboflavin, and B12.
* The cardio-metabolic part of the testing includes homocysteine (price is a little higher for cardio markers but well worth it)

Do I need MTHFR testing and Do I need folate?
The answer is YES! Most people need MTHFR testing, BUT you should only take folate and methylated b12 or hydroxy b12 IF homocysteine is high and folate and/or b12 are low. If high homocysteine is not treated, it can lead to heart disease.

Can I just folic acid? The answer is No. Folic acid cannot be converted to the usable form of methylated folate so it can build up in the body and raise homocysteine levels which can lead to heart disease.

So……………..MTHFR Testing: Do I Need It and Do I Need Folate? Most everyone should get tested to get answers to prevent an unnecessary health problem in life!

Personal Story: As I aged my homocysteine levels went up. Of course, I too got my blood tested and found that my homocysteine levels along with insulin levels were pretty high. I immediately went on folate, and hydroxy b12 and my levels improved. I eat well, love life, but we have a genetic issue with MTHFR, if I can have it so can you! One of my children had a blood clot, he is fine, he had a double gene deficiency, taking folate he noticed improvements in his health and even in his veins.

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Medical disclaimer: Our tests cannot be used to diagnose, treat or cure any disease. All test results are to be used as educational materials and as a guide to help support your overall health and wellness. Always discuss health concerns with your medical doctor.