By Alane Palmer, ND, CNC
When adrenal fatigue begins to effect the body it starts out with the adrenal hormones of cortisol, DHEA and pregnenalone increasing and then in the later stages of adrenal fatigue the levels drop. On the top of the list of the hormones that effect adrenal health are: cholesterol, then pregnenalone, then Aldosterone / DHEA / Progesterone, then Cortisol / Androstenedoine and so on. Pregnenalone is needed in optimal levels to help make estrogen, testosterone and progesterone. It is also needed to support proper sodium regulation and inflammation.
When there is stress the adrenals will look to cortisol production to be much higher which needs pregnenalone to be higher too. If pregnenalone is not able to keep up with its needs adrenal fatigue may set in along with cortisol depletion.
Pregnenalone can help boost energy levels, improve mood and focus, sleep quality, reduced inflammation, enhance immune response, improve skin quality and wound healing, improve libido, along with give the person an overall sense of wellness which improves stress tolerance. Pregnenalone is also an anti-aging support.
Thus, pregenalone is one of several important hormones needed to help reduce or eliminate adrenal fatigue. Testing for adrenal fatigue is important so you know the best supports to enhance health, wellness and energy. This can be done via saliva cortisol testing which includes cortisol x4, 17-OH pregnenalone and DHEA-S.
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Medical disclaimer: Testing for adrenal fatigue and other test kits cannot be used to diagnose, treat or cure any disease. All test results are to be used as educational materials and as a guide to help support your overall health and wellness. Always discuss health concerns with your medical doctor.
“Hormones, Are They What Causes Fatigue? Find Out!”. Drlam.com. N.p., 2012. Web. 14 July 2016.