IBSSure / SIBO Test

$269.00

IBSSureTM is a simple blood test (sibo test) that detects two antibodies which are indicative of bacterial-pathogen-induced motility dysfunction, which can lead to increased incidence of SIBO.

Anti Vinculin ab
Anti – Cytolethal Distending Toxin BIGG

SIBO plain and simple: A toxin is released most likely due to food poisoning which is called Cytolethal Distending Toxin. You may feel like you have an “acute” gastro infection. This toxin causes antibodies to be produced which causes an autoimmune type of reaction. This process slows down the bacteria cleansing process called the Migrating Motor Function.

It is normal to have some bacteria in the small intestine, but when it reaches over 105-106 organisms / ml it is out of range and  out of control. Basically the bacteria in the large intestine has moved to the small intestine and is out of control and in the wrong place.

Description

IBS is a commonly occurring collection of symptoms diagnosed in the world of gastroenterology. It is the most common GI disorder with worldwide prevalence rates ranging from 10-15%. There are between 2.4 and 3.5 million physician visits annually for IBS in the US. Recent research has shown that up to 84% of those with an IBS diagnosis test positive for  Small Intestinal Bacterial Overgrowth. (SIBO Test)

Breath tests for Small Intestinal Bacterial Overgrowth (SIBO) can be very time consuming for patients, as well as inaccurate, due to many factors.
Glucose Breath Testing: 62% sensitivity / 81 % specific
Lactose Breath Testing: 52% sensitivity / 85 % specific

IBSSureTM is a simple blood test that detects two antibodies which are indicative of bacterial-pathogen-induced motility dysfunction, which can lead to increased incidence of SIBO.
CdtB toxins (cytolethal distending toxin B) are released by gastroenteritis-causing bacteria, against which antibodies are produced by the immune system. These antibodies interact with a protein, vinculin, present in the intestinal cell-lining matrix. This interaction compromises and impairs digestive motility. This pathological breakdown of the gastrointestinal motility complex is foundational to chronic SIBO development and recurrence and has been well-studied and documented.

SIBO does not happen to only people with GI symptoms!

Illnesses that can be associated with SIBO:
Autoimmunity, Chronic Fatigue Syndrome, Ehler’s Danlos, H Pylori, Osteoporosis, Renal Failure, Malabsorption)

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